Dr. Michael F. Holick, Ph.D., M.D.
Dr. Michael F. Holick

’The D-Lightful Vitamin D for Good Health‘, from I.H.M.C. lecture, published March 16, 2013

Posted by admin on April 1, 2013 under Arthritis, Cancer, Case Files, Diabetes, Infectious Disease, Multiple Sclerosis, Obesity, Osteomalacia, Osteoporosis, Rickets, Vitamin D | Be the First to Comment

View the latest video clip of Dr. Holick speaking about  …’The D-Lightful Vitamin D for Good Health‘, from I.H.M.C. lecture, published March 16, 2013 – click here to view the video clip:   http://www.youtube.com/watch?v=hiGBVDcbFVk&feature=youtu.be

“Influence of Vitamin D Status and Vitamin D3 Supplementation on Genome Wide Expression of White Blood Cells: A Randomized Double-Blind Clinical Trial”

Posted by admin on under Arthritis, Cancer, Case Files, Diabetes, Infectious Disease, Multiple Sclerosis, Obesity, Osteomalacia, Osteoporosis, Rickets, Vitamin D | Be the First to Comment

Influence of Vitamin D Status and Vitamin D3 Supplementation on Genome Wide Expression of White Blood Cells:  A Randomized Double-Blind Clinical Trial” was recently published in PLOS ONE and is available online by clicking here to view:  http://dx.plos.org/10.1371/journal.pone.0058725

Diabetes and Vitamin D

Posted by admin on November 27, 2008 under Diabetes, Vitamin D | 6 Comments to Read

Diabetes mellitus type I

Studies in mice have suggested that pretreating mice that are prone to developing type I diabetes with the active form of vitamin D (1,25-hydroxyvitamin D [1,25(OH)2D]) reduces the development of type I diabetes by 80%.  This study is supported by the observation in Finland where children in the 1960’s routinely received 2,000 IU of vitamin D a day during their first year of life.  When these children were followed for the next 31 years, it was observed that these children had a reduced risk of developing type I diabetes by 78%.  Children who were vitamin D deficient at the same time and also followed for 31 years had an almost 300% increased risk of developing type I diabetes.  

Reference:

Hypponen E, Laara E, Jarvelin M-R, Virtanen SM.  Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study.  Lancet 2001;358:1500-1503.

Diabetes mellitus type II

The beta islet cells that produce insulin in the pancreas have a vitamin D receptor.  The active form of vitamin D stimulates the pancreas to produce insulin.  It has been observed that the relative risk of developing type II diabetes is reduced by as much as 33% in men and women who increase their intake of vitamin D above 800 IU/day along with 1,000 milligrams of calcium.  

Reference:

Pittas AG, Dawson-Hughes B, Li T, et al.  Vitamin D and calcium intake in relation to type 2 diabetes in women.  Diabetes Care 2006:29:650-56.