Posted by admin on April 1, 2013 under Arthritis, Cancer, Case Files, Diabetes, Infectious Disease, Multiple Sclerosis, Obesity, Osteomalacia, Osteoporosis, Rickets, Vitamin D | 
View the latest video clip of Dr. Holick speaking about …’The D-Lightful Vitamin D for Good Health‘, from I.H.M.C. lecture, published March 16, 2013 – click here to view the video clip: http://www.youtube.com/watch?v=hiGBVDcbFVk&feature=youtu.be
Posted by mfholick on March 6, 2009 under Cancer, Multiple Sclerosis, Osteomalacia, Osteoporosis, Rickets, Vitamin D |
VITAMIN D AND DISEASE STATES
EPILEPSY
I have heard that vitamin D may play a role in epilepsy, possibly due to interaction with anti-epileptic drugs. Is this becoming an acknowledged effect? And how much vitamin D is necessary to combat the interaction to reduce seizures?
Response: Epileptic drugs will enhance the destruction of vitamin D making patients who are on anti-seizure medications at higher risk for developing vitamin D deficiency and osteomalacia or rickets. Measurement of 25-hydroxyvitamin D [25(OH)D] is important in patients on antiepileptic medications. Often twice as much vitamin D is required to maintain a blood level of 25(OH)D of > 30 ng/ml. Thus, 2,000-4,000 IU of vitamin D/d is usually needed. An alternative is to take 50,000 IU of vitamin D2 either once every week or once every two weeks depending on the serum 25-hydroxyvitamin D level.
MENTAL HEALTH
What is your position on vitamin D and depression and schizophrenia?
Response: There is evidence that vitamin D deficiency during pregnancy increases the risk of the child developing schizophrenia during their adult life. There is also evidence that vitamin D receptors exist in the brain, and that the active form of vitamin D, 1,25-dihydroxyvitamin D, Read more of this article »
Tags: ALS, Autoimmune Diseases, cancers, Epilepsy, Kidney Disease/Dialysis, Mental Health, Multiple Sclerosis, Osteomalacia, osteopenia, Osteoporosis, Rickets, thyroid
Posted by admin on November 27, 2008 under Multiple Sclerosis, Vitamin D |
It is known that if you are born above 35° latitude at approximately Atlanta, Georgia, and live at this latitude for the first ten years of your life that you have a 100% increase risk of developing multiple sclerosis. Recent studies have suggested that women and men who increase their vitamin D intake above 400 IU of vitamin D a day reduces risk of developing multiple sclerosis by approximately 40%.
References:
Munger KL, Zhang SM, O’Reilly E, Hernan MA, Olek MJ, Willett WC, Ascherio A. Vitamin D intake and incidence of multiple sclerosis. Neurology 2004; 62(1):60-5.
Munger KL, Levin LI, Hollis, BW, Howard NS, Ascheino A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006; 296:2832-2838.
Ponsonby A-L, McMichael A, and van der Mei I. Ultraviolet radiation and autoimmune disease: insights from epidemiological research. Toxocology 2002;181-182:71-78.
